ʻO nā poʻo a me nā neʻe hiki ke lilo i mau hōʻailona neʻokeʻo e hiki ai ke kuhikuhi i ka maʻi o ka lolo, ka maʻi ʻona a me nā maʻi autoimmune paha. He mea nui ka maʻi Diagnosis akā hiki i ka hana ke koi i nā hola he nui.

ʻO kēia ka wehewehe ʻana o kahi hoʻāʻo i kūkulu ʻia e nā mea noiʻi o ke Kulanui ʻo Jefferson e ʻike koke i kahi maʻi lolo a i ʻole nā ​​pilikia i ka spinal kaula.

kumu: MEDICA tradefair a ʻO Thomas Jefferson University

"He nui nā ho'āʻo no ka hanaʻana i nā diagnostics, akā,ʻo ka mea i hōʻike pinepine i ka maʻi, hiki ke lawe i ka manawa aʻoi aku ka manawa ma mua o kā mākou makemake, a ma nā hihia o ka maleingitis a me ka'ecephalitis'ōpiopio," wahi a Mark Curtis, MD, PhD, Polokelē Hoʻokele o Pathology, Anatomy a me Cell Cell Biology, aʻo ia hoʻi ka mea hana ma keʻano he mea lapaʻau hōkele. "I ka hōʻoiaʻiʻoʻiaʻana me nā noiʻi hou, hiki i kā mākou hōʻoia ke hāʻawi i kahi ala mua, wikiwiki a me keʻano haʻahaʻa e nānā i nā mea e hana nei ma ka lolo a alakaʻi i ke kālaʻau aiʻole i nā hōʻolo hou."

Ma mua o ka ho'āʻoʻana no ka heleʻana o ka huakiki a huakani paha, ua nānā nā mea noiʻi i nā mea hōʻailona mua o ka maʻi:ʻo nā cytokines i hanaʻia e ka pūnaewele mālamaʻole o ka maʻi i pane i nā maʻi pathogens a me nā hanaʻeha. "ʻO Cytokines he pūnaha hōʻailona ma ke kino," wahi a Dr. Curtis. "Hoʻonāukiuki nā mea hana hewa i kahi pane pāʻani mahaʻole, kahi kī nui o ka hoʻokuʻuʻiaʻana o nā hui likeʻole o nā cytokines i hoʻolālāʻia e kū'ē i nā maʻi pathogens. ʻO nā hoʻololiʻana i nā kūmole o ka cytokine o ka wai o ka momona e hāʻawi mai i kahi hōʻaiho mua o ka maʻi. "

Ua hoʻoholo ʻo Dr. Curtis a me nā hoa hana i ʻike inā hiki iā lākou ke ʻike i nā hiʻohiʻona i loko o nā cytokines e ʻokoʻa ke ʻano ʻokoʻa i nā maʻi ʻeha ʻē aʻe a i ʻole a maʻi. ^ E Ha yM. Ma ka loiloi retrospective, nānā nā mea noiʻi i nā hoʻohālike i hōʻuluʻulu ʻia mai nā maʻi maʻi 43 i loaʻa i nā pā kuʻi i ka wā o ko lākou halemai e noho nei. A laila hoʻāʻo ka poʻe noiʻi i ka lolo o ka spinal cerebral (CSF) no ka loaʻa ʻana o ka 41 mau cytokine ʻokoʻa a ʻike ke ʻike ʻia nā maʻi me ka maʻi neʻe o ka pūnae ma waena o ka ʻōiwi poloka e like ai me kahi maʻi tumō a manu ʻole. Ua hōʻike kēia i ka hōʻike hiki ke hoʻohana i ka haʻi ʻē aʻe.

Eia kekahi, i loko o nā mea maʻi i hōʻike ʻia me ka maʻi o ka lolo, ua ʻokoʻa ka CSF cytokine fingerprint i nā hanana o ka maʻi maʻi i hoʻohālikelike ʻia i nā poʻe me nā pathogens ʻaʻole viral, e like me nā mea maʻi a me nā fungi.

"Me ka liʻiliʻi liʻiliʻi o ka wai spinal e pono ai, hiki ke hoʻohana ʻia ka CSF cytokine analysis ma ke ʻano he hoʻokahi o nā hoʻokolohua diagnostic mua i ka wikiwiki. ke hele nā pilikia koʻikoʻi o ke kikowaena pūnaewele a alakaʻi i ka hana koke ʻana, "wahi a ka mea kākau mua, ʻo Danielle Fortuna, MD, he Kumu Kokua, ma ke Keʻena ʻo Pathology a me Laboratory Medicine, ma ka Halemai o ke Kulanui o Pennsylvania e pili ana i kahi maʻi lolo.

Ma ke ao holoʻokoʻa,ʻoi aku ka nui o kaʻehā miliona mau mākua a me nā keiki i kēlā me kēia makahiki. "ʻO nā keiki pēpē a me nā keiki liʻiliʻi he nui ka nui o ka maningitis a me ka encephalitis a me nā mea pili, he nui ke koʻikoʻi," wahi a Dr. Curtis. "ʻO ka hikiʻana ke hoʻomaopopo koke i kahi maʻi o nā pūpū o nā pūpū ma keʻano he pilikino hiki ke hana nui i ka pane wikiwikiʻana."

"ʻO ka mea'ē aʻe, hiki i ka hōʻoia keʻike i ka viral mai nā maʻi non-viral, kahi wehewehe e hiki ai ke hoʻopakele i kahi keiki me ka maʻi viral mai kahi hanaʻole o nā lāʻau'alopelo, a kau i ka mālama i nā hana antiviral a me nā kōkua e like me ka mea e pono ai," wahi a Dr. Curtis . "ʻO ka neʻeʻana i mua,ʻo kā mākou pahuhopuʻo ia ke hōʻoia kūpono i kā mākou mau hopena ma kahi hōʻailona nui aʻe e komo ai nā mākua a me nā keiki no ka hoʻohana houʻana i ka pānaʻi clinical."