Protective Gene Discovered Against Alzheimer's
Ib txoj kev tshawb fawb Columbia University qhia txog cov noob uas txo cov kev pheej hmoo ntawm Alzheimer's txog li 70%, paving txoj kev rau kev kho tshiab
Ib qho Kev Tshawb Fawb Zoo Tshaj Plaws
Ib qho extraordinary breakthrough nyob rau hauv Kev kho mob Alzheimer tau ua rau muaj kev cia siab tshiab los daws tus kab mob. Cov kws tshawb fawb ntawm Columbia University tau txheeb xyuas cov noob uas txo qhov kev pheej hmoo ntawm kev tsim Alzheimer's txog li 70%, qhib lub peev xwm tshiab cov hom phiaj kho.
Lub luag haujlwm tseem ceeb ntawm Fibronectin
Cov tshuaj tiv thaiv kab mob sib txawv yog nyob hauv cov noob uas tsim tawm fibronectin, ib qho tseem ceeb ntawm cov ntshav-hlwb barrier. Qhov no txhawb nqa qhov kev xav tias cov hlab ntsha hlwb ua lub luag haujlwm tseem ceeb hauv Alzheimer's pathogenesis thiab tuaj yeem yog qhov tseem ceeb rau kev kho tshiab. Fibronectin, feem ntau tam sim no nyob rau hauv tsawg qhov ntau hauv cov ntshav-hlwb barrier, zoo nkaus li siv zog tiv thaiv Alzheimer's los ntawm tiv thaiv ntau dhau ntawm cov protein no hauv daim nyias nyias.
Kev cog lus kho tau zoo
raws li Caghan Kizil, tus thawj coj ntawm txoj kev tshawb fawb, qhov kev tshawb pom no tuaj yeem ua rau kev txhim kho cov kev kho tshiab uas ua rau muaj kev tiv thaiv ntawm cov noob. Lub hom phiaj yog los tiv thaiv lossis kho Alzheimer's los ntawm kev siv cov fibronectin lub peev xwm tshem tawm cov co toxins los ntawm lub hlwb los ntawm cov hlab ntsha-hlwb barrier. Qhov kev xav kho tshiab no muaj kev cia siab rau ntau lab tus tib neeg cuam tshuam los ntawm tus kab mob neurodegenerative no.
Richard Mayeux, tus thawj coj ntawm txoj kev tshawb fawb, qhia qhov kev cia siab ntawm kev cia siab rau yav tom ntej. Cov kev tshawb fawb ntawm cov qauv tsiaj tau lees paub qhov ua tau zoo ntawm fibronectin-targeted therapy hauv kev txhim kho Alzheimer's. Cov txiaj ntsig no ua rau txoj hauv kev rau txoj kev kho mob uas muaj peev xwm ua kom muaj zog tiv thaiv kab mob. Tsis tas li ntawd, kev txheeb xyuas qhov kev tiv thaiv no tuaj yeem ua rau muaj kev nkag siab zoo dua ntawm cov txheej txheem hauv qab ntawm Alzheimer's thiab nws txoj kev tiv thaiv.
Dab tsi yog Alzheimer's
Alzheimer's yog ib qho mob tsis zoo ntawm lub hauv nruab nrab lub paj hlwb uas cuam tshuam nrog kev poob qis hauv kev txawj ntse, kev nco, thiab kev paub txog kev xav.. Nws yog hom dementia ntau tshaj plaws, feem ntau cuam tshuam rau cov neeg laus, txawm hais tias nws tuaj yeem tshwm sim thaum muaj hnub nyoog me me hauv qhov tshwj xeeb. Lub cim tseem ceeb ntawm Alzheimer's dag nyob rau hauv lub xub ntiag ntawm amyloid plaques thiab tau protein ntau tangles nyob rau hauv lub hlwb, uas ua rau puas thiab puas hlwb hlwb. Qhov no ua rau cov tsos mob xws li tsis nco qab, tsis meej pem hauv hlwb, teeb meem hauv kev hais lus thiab kev xav, nrog rau teeb meem kev coj cwj pwm thiab kev xav. Tam sim no, tsis muaj kev kho mob rau tus kab mob no, tab sis kev tshawb fawb txuas ntxiv mus nrhiav cov kev kho mob tshiab txhawm rau txhawm rau txo qis kev loj hlob ntawm tus mob thiab txhim kho lub neej zoo rau cov neeg mob. Kev tshawb pom ntawm qhov kev tiv thaiv no yog qhov tseem ceeb hauv kev tawm tsam qhov kev puas tsuaj loj no.
Qhov chaw