Iyo Yakakosha Basa reGuanine muDNA uye RNA
Kuwana kukosha kweimwe yeMana Yakakosha Nucleotides yeHupenyu
Chii chinonzi Guanine?
Chimwe chezvivakwa zvina zvakakosha zveDNA neRNA ndizvo guanine. Iyo yakakosha nitrogen-ine komisheni inobatana neadenine, cytosine, uye thymine (kana uracil muRNA) kugadzira iyo genetic code. Chii chinoita kuti guanine ive yakasarudzika maitiro ayo akaomarara: kusanganiswa kwepyrimidine uye imidazole zvindori, kugadzira purine komputa. Formula yaro ndeye C5H5N5O.
Zvenyama uye Zvimiro
Guanine inoratidzika sehupfu chena uye ine nzvimbo yakanyanyisa kunyungudika, inosvika 360°C. Izvi zvinodaro nekuti makristasi ayo anobatwa pamwechete neakasimba mabhondi ehydrogen. Kunyangwe isinganyungudika mumvura, guanine inogona kunyungudutswa mu diluted acids kana mabhesi. Huremu hwayo hwemamorekuru i151.13 g/mol, uye huremu hwayo hwakaverengerwa hwakakura 2.200 g/cm³.
Biological Function uye Applications
Pasina guanine, hupenyu hungadai husipo. Inoumba chisungo chakasimba ne cytosine muDNA neRNA kuburikidza nematatu ehydrogen bond. Izvi zvinodzikamisa yakakurumbira mbiri helix chimiro uye inova nechokwadi chekudzokorora kweDNA. Asi mabasa eguanine haagumiri ipapo. Zvinobva pairi, senge GTP (guanosine triphosphate), inoita mabasa akakosha mumaserura maitiro sekusaina uye kugadzirwa kweprotein.
Guanine ndeyeboka rinonzi purine bases, zvakakosha zvikamu zveDNA uye RNA mamorekuru.
The Discovery Nyaya
Mugore riri kure ra1844, muGermany kemisitiri anonzi Julius Bodo Unger yakatanga kuwanikwa guanine. Chinhu chinoshamisa? Akaitora kubva muguano, nokudaro zita rayo. Nokufamba kwenguva, masayendisiti akadzidza zvakawanda nezvechimiro cheguanine uye basa rayo rinokosha mugenetics uye molecular biology.
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