Khamriga iyo arrhythmogenic wadnaha wadnaha saxda ah ee wadnaha

By Cristiano Antonino On Aug 9, 2022

'Cardiomyopathy' waa erey guud oo loogu talagalay cudurka asaasiga ah ee muruqa wadnaha (myocardium)

Dhaawaca myocardial ee ka yimaada cudurrada halbowlaha halbowlaha iyo dhiig-karka ayaa mas'uul ka ah inta badan cudurrada wadnaha

Qaybtan goobta, waxaan ka wada hadli doonaa cudurada myocardial ee aan ischaemic iyo non-hypertensive asal ahaan, kuwaas oo ka masuul ah ku dhawaad 5-10 ee xaaladaha wadnaha oo aan shaqayn.

Kooxdan waxaa ka mid ah:

isku-darka wadnaha iyo xididada
hypertrophic wadnaha wadnaha;
xanuunka wadnaha ee xaddidan;
wadnaha wadnaha ee khamriga;
arrhythmogenic wadnaha wadnaha saxda ah;
myocarditis.

Wadna xanuunka khamriga

Yurub iyo Maraykanka, isticmaalka khamriga culus ee muddada dheer waa sababta ugu weyn ee aan ischaemic DCM ahayn.

Guud ahaan, bukaanka khamriga ah ee isticmaala in ka badan 90 g oo khamri ah maalintii (qiyaastii todoba ilaa siddeed cabitaan caadi ah maalintii) in ka badan shan sano waxay halis ugu jiraan inay yeeshaan asymptomatic aalkolada wadnaha.

Marka la isticmaalo aalkolo wakhti dheer oo dheeraad ah, cudurka wadnaha waxaa laga yaabaa inuu horumaro oo uu keeno calaamadaha iyo calaamadaha wadne-gabka.

Wadna xanuunka alkoholka waxa lagu gartaa korodhka cufnaanta myocardial, balaadhinta xididdada dhiigga iyo dhumucda parietal.

Isbeddellada ku dhaca shaqada ventricular waxay ku xiran yihiin marxaladda: asymptomatic alkoholic cardiomyopathy waxay la xiriirtaa cillad la'aanta diastooliga, halka cilladda systolic ay tahay wax caadi ah oo laga helo bukaannada calaamadaha leh.

Arrimaha pathophysiological ee xaaladdan waa kuwo adag.

Saddexda hab ee ugu waaweyn ee la soo jeediyay waa:

Saamaynta sunta tooska ah ee khamriga ee myocytes
saamaynta nafaqeynta (inta badan thiamine yaraan),
waxyeelada sunta ah ee lagu daro cabitaanka khamriga (cobalt-induced cardiomyopathy ee Kanada dhowr sano ka hor).

Dumarku waxay u muuqdaan inay ka dareen badan yihiin ragga marka loo eego saamaynta wadnaha ee khamriga iyo iyaga qiyaasta wadarta nolosha ee ethanol ee hoose ayaa ku filan inay qaadaan cudurka.

Inkastoo xaqiiqda ah in celceliska qiyaasta nolosha ee khamriga ee haweenka khamriga ah uu ka hooseeyo ragga khamriga ah, wadnaha wadnaha iyo myopathy ayaa u muuqda inay si siman u badan yihiin.

Natiijooyinka baaritaanka ujeeddadu waxay la mid yihiin kuwa lagu arkay DCM laakiin way ku kala duwan yihiin ku lug lahaanshaha hal ama labadaba halbowlayaasha iyo heerka cillad la'aanta myocardial.

Saamaynta adrenergic ee isticmaalka khamriga awgeed, dhacdooyinka tachyarrhythmia supraventricular ayaa kordhay.

Ka fogaansho la'aanta daawaynta daroogada ee wadne-gabnimada waxay u horseedi kartaa horumar waara shaqada ventricular iyo saadaalinta.

QALABKA ECG? BOOQO BOOTHKA ZOLL EE BANDHIGGA DEGDEGGA AH

Bukaanka qaba wadnaha wadnaha waxaa laga yaabaa inay soo bandhigaan natiijooyin la mid ah kuwa bukaanada qaba IDCM

Khamriga oo aan lahayn ka-hortagnaan la'aan waa saadaal xooggan oo saadaalisa dhimashada hore ee wadnaha.

Sidaa darteed, hab dagaal leh ayaa loo baahan yahay bukaankan si loo gaaro joojinta isticmaalka khamriga.

ILAALINTA KAARDIYADA IYO BADBAADINTA CARDIOPULMONARY? BOOQO BUUGGA EMD112 EE IMTIXAANKA DEGDEGGA HADDII FAAHFAAHIN DHEERAAD AH

Arrhythmogenic wadnaha wadnaha ee saxda ah

Wadnaha wadnaha ee wadnaha ee Arrhythmogenic ama Dysplasia (ARVC, ARVD) waxaa lagu gartaa bedelka fibroadipose ee myocardium ventricular midig.

Waa cudur ku dhaca autosomal oo ay ku badan yihiin ragga.

ARVC waa mid ka mid ah sababaha ugu horreeya ee dhimashada degdega ah ee dhalinyarada qaangaarka ah iyo ciyaartoyda, gaar ahaan woqooyi-bari ee Talyaaniga, marka la barbardhigo, si yar ayaa loogu arkaa Maraykanka.

ARVC waxaa lagu gartaa spectrum phenotypic ballaaran, oo leh luminta myocytes inta lagu jiro korriinka hore ee myocardium ventricular midig oo leh adipose ama beddelka fibros.

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Samaynta halbowlayaasha aneurysm-ka midig iyo cilladaha kinetic-ka ee qaybeed waxay matalaan shuruudo kale.

ARVC waxay inta badan la xiriirtaa myocarditis.

Cilad-sheegid caafimaadku waa dhibaato.

Bukaan-socodka ayaa laga yaabaa inay ka cawdaan garaaca wadnaha ama isku-dhafka inta badan iyadoo lala xiriirinayo arrhythmias dib-u-soo-noqoshada ah.

Cilad-sheegidda waxaa laga yaabaa in lagu sameeyo taariikhda qoyska, tachyarrhythmia ventricular, gaar ahaan tachycardia ventricular midig ee ay keento sii deynta catecholamine ee jimicsiga.

Natiijooyinka ECG-ga caadiga ah waxaa ka mid ah rogidda T-wave ee horseedda hore ee V1 ilaa V3 iyo hirarka epsilon.

Echocardiography waxa ay tilmaami kartaa fidinta ventricular-ka ee saxda ah, cilladaha kinetic ee qaybta qaybta ama samaynta aneurysm.

Si kastaba ha ahaatee, shuruudaha sawirka ARVC waxaa si fiican u qiimeeyay RMC sababtoo ah sawirka sare ee qaab dhismeedka ventricular saxda ah iyo shaqada iyo sifada unugyada loo isticmaalo in lagu aqoonsado adipose dhexgalka myocardium.

Daaweynta ka hortagga arrhythmic ee leh beta-blockers ama amiodarone ayaa loo isticmaalaa in lagu caawiyo xakamaynta arrhythmias iyo, bukaanada khatarta sare ugu jira dhimashada degdega ah, daawaynta ICD waxay ka ilaalin kartaa nafta halis geliya arrhythmias ventricular.

Ciyaartoyda qaba cudurka ARVC ee suurtogalka ah ama qaarkood waa in laga saaraa inta badan dhaqdhaqaaqyada ciyaaraha tartanka.