ʻO ke kuleana koʻikoʻi o Guanine ma DNA a me RNA
Ka ʻike ʻana i ke koʻikoʻi o kekahi o nā nucleotides kumu ʻehā no ke ola
He aha ka Guanine?
ʻO kekahi o nā papa hana nui ʻehā o DNA a me RNA guanine. ʻO ia kahi pūhui naikokene kūikawā e hui pū me ka adenine, cytosine, a me thymine (a i ʻole uracil i RNA) e hana i ke code genetic. ʻO ka mea e ʻokoʻa ai ka guanine ʻo kona ʻano paʻakikī: kahi hui o nā apo pyrimidine a me nā imidazole, e hana ana i kahi purine purine. ʻO kāna kumu C5H5N5O.
Nā Pono Kino a me ke Kino
ʻIke ʻia ʻo Guanine ma ke ʻano he pauka keʻokeʻo maʻalahi a he wahi heheʻe kiʻekiʻe loa kona, ma kahi o 360°C. ʻO kēia ke kumu no ka paʻa ʻana o kāna mau kristal e nā paʻa hydrogen ikaika. ʻOiai ʻaʻole ia e hoʻoheheʻe i ka wai, hiki ke hoʻoheheʻe ʻia ka guanine i nā ʻakika i hoʻoheheʻe ʻia. ʻO kona kaumaha molekala he 151.13 g/mol, a he 2.200 g/cm³ ka nui i helu ʻia.
Nā hana olaola a me nā noi
Inā ʻaʻohe guanine, ʻaʻole ola ke ola. Hoʻokumu ia i kahi paʻa ikaika me ka cytosine i DNA a me RNA ma o ʻekolu mau paʻa hydrogen. Hoʻopaʻa kēia i ke ʻano helix pālua kaulana a hōʻoia i ka hoʻopiʻi DNA pololei. Akā, ʻaʻole pau nā hana a guanine ma laila. ʻO kāna mau derivatives, e like me GTP (guanosine triphosphate), pāʻani i nā hana koʻikoʻi i nā kaʻina kelepona e like me ka hōʻailona a me ka hana protein.
Aia ʻo Guanine i kahi pūʻulu i kapa ʻia nā kumu purine, nā ʻāpana koʻikoʻi o nā molekole DNA a me RNA.
Ka Moʻolelo ʻIke
I ka makahiki lōʻihi o 1844, ua kapa ʻia kekahi kanaka kemika Kelemania ʻO Julius Bodo Unger ʻike mua ʻia ka guanine. ʻO ka mea ʻokoʻa? Ua unuhi ʻo ia mai ka guano, no laila kona inoa. I ka wā lōʻihi, ua aʻo hou ka poʻe ʻepekema e pili ana i ke ʻano o ka guanine a me kāna kuleana koʻikoʻi i ka genetics a me ka molecular biology.
kumu