Dziviriro Gene Yakawanikwa Kurwisa Alzheimer's
Chidzidzo cheColumbia University chinoratidza jini rinoderedza njodzi yeAlzheimer's kusvika 70%, ichigadzira nzira yekurapa kutsva.
Kuwanikwa Kunoshamisa Kwesainzi
Kubudirira kunoshamisa mukati Kurapa kweAlzheimer kwaunza tariro itsva dzekugadzirisa chirwere ichi. Vatsvagiri veColumbia University vakaona geni iro inoderedza njodzi yekuva neAlzheimer's kusvika ku70%, kuvhura nzira itsva dzekurapa dzakanangwa.
Basa Rakakosha reFibronectin
Iyo inodzivirira genetic musiyano inowanikwa mune gene rinogadzira fibronectin, chikamu chinokosha cheropa-brain barriers. Izvi zvinotsigira fungidziro yekuti tsinga dzeuropi dzinoita basa rakakosha muAlzheimer's pathogenesis uye inogona kuve yakakosha pakurapa kutsva. Fibronectin, inowanzovapo muhuwandu hushoma mune ropa-brain brain, inoita seinodzivirira kubva kuAlzheimer's by kudzivirira kuunganidzwa kwakanyanya kweprotein iyi mu membrane.
Kuvimbisa Kurapa Tarisiro
Maererano ne Caghan Kizil, mutevedzeri wemutungamiri wekudzidza, kuwanikwa uku kunogona kutungamirira kukugadzirwa kwemishonga mitsva inotevedzera maitiro ekudzivirira ejini. Chinangwa chingave chekudzivirira kana kurapa Alzheimer's nekushandisa fibronectin kugona kubvisa chepfu kubva muuropi kuburikidza neropa-brain barriers. Aya maonero matsva ekurapa anopa tariro yakasimba kumamirioni avanhu vakabatwa nechirwere ichi cheurourodegenerative.
Richard Mayeux, mutungamiriri pamwe chete wefundo yacho, anoratidzira tarisiro pamusoro pekariro dzomunguva yemberi. Zvidzidzo zvemhando dzemhuka zvakasimbisa kushanda kwefibronectin-yakananga kurapa mukuvandudza Alzheimer's. Mhedzisiro iyi inovhura nzira yekurapa kwakanangwa kunogona kupa dziviriro yakasimba pachirwere. Pamusoro pezvo, kuzivikanwa kweiyo mutsauko wekudzivirira kunogona kutungamirira kunzwisiso iri nani yenzira dziri pasi peAlzheimer's nekudzivirira kwayo.
Chii chinonzi Alzheimer's
Alzheimer's chirwere chisingaperi chinodzikira chepakati tsinga system chinosanganisira kuderera kunofambira mberi mukugona kwekuziva, ndangariro, uye hunyanzvi hwekuita.. Ndiyo nzira yakajairika yedementia, inonyanya kubata vanhu vakura, kunyangwe ichigona kuratidzira pazera diki muzviitiko zvakasarudzika. Mucherechedzo weAlzheimer's uri mukuvapo kwemaamyloid plaques uye tau protein tangles muuropi, izvo zvinokonzeresa kukuvadzwa nekuparadzwa kwemasero etsinga. Izvi zvinoguma nezviratidzo zvakadai sokurasika kwendangariro, kuvhiringidzika mupfungwa, kuomerwa mukutaura uye kurongeka kwekufunga, pamwe chete nezvinetso zvetsika nendangariro. Parizvino, hapana mushonga chaiwo wechirwere ichi, asi kuedza kwetsvakiridzo kunoenderera mberi nekutsvaga marapirwo matsva ane chinangwa chekudzikisira kufambira mberi kwechirwere uye kuvandudza hupenyu hwevarwere. Kuwanikwa kweichi mutsauko unodzivirira nokudaro kunoumba danho rakakosha mukurwisa ichi chinoparadza.
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